Human chorionic gonadotropin (hCG) is ahormone preparations used to treat infertility or infertility in women. This drug is available in injectable form.
Naturally, the hormone hCG will be produced by the placenta in early pregnancy to keep the corpus luteum producing progesterone. The hormone progesterone is needed in early pregnancy to maintain the uterine lining.
In contrast to its function during pregnancy, preparations of the hormone human chorionic gonadotropin (hCG) are used to trigger egg maturation and ovulation.
This drug will also trigger the testes to produce the hormone testosterone, so it can be used to treat hypogonadism and stimulate descent of the testicles into the testicles in boys with cryptocystis.
Trademarkhuman chorionic gonadotropin: Ovidrel, Pregnyl
What is Human Chorionic Gonadotropin
| Category | Hormone |
| group | Prescription drugs |
| Benefit | Used in the treatment of infertility in women, increases sperm count and testosterone in men, and treats cryptorchidism in boys. |
| Used by | Adults and children |
| Human chorionic gonadotropin (HCG) for pregnant and lactating women | Category X:Studies in experimental animals and humans have demonstrated fetal abnormalities or a risk to the fetus. Drugs in this category should not be used in women who are or may become pregnant. It is not known whether Human chorionic gonadotropin can be absorbed into breast milk or not. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Drug form | Inject |
Precautions Before Using Human Chorionic Gonadotropin
Human chorionic gonadotropin should only be used according to a doctor's prescription. Before using human chorionic gonadotropin, you need to pay attention to the following points:
- Tell your doctor about your history of allergies. Human chorionic gonadotropin should not be given to patients who are allergic to this drug.
- Tell your doctor if you have premature puberty, migraines, thyroid disease, asthma, seizures, adrenal gland disease, prostate cancer, breast cancer, brain tumor, or vaginal bleeding for which there is no known cause.
- Tell your doctor if you have ever had liver disease, blood clotting disorders, heart disease, or lung disease.
- Tell your doctor if you are pregnant or breastfeeding. Although it is used to treat infertility, hCG should not be used by pregnant women, because it can increase the risk of congenital defects in the fetus.
- Tell your doctor if you are taking certain medications, supplements, or herbal products.
- See your doctor right away if you experience an allergic drug reaction, overdose, or serious side effect after using human chorionic gonadotropin.
Dosage and Instructions for Use of Human Chorionic Gonadotropin
Human chorionic gonadotropin (hCG) injection will be given under the skin (subcutaneously/SC) or into the muscle (intramuscular/IM). The dose of human chorionic gonadotropin (hCG) varies from patient to patient, depending on the condition being treated, its severity, and the patient's response to the drug.
In general, the following is the division of HCG doses based on the purpose of treatment:
- Purpose: Overcoming infertility in women
Mature: 5,000–10,000 units, once a day. The follow-up dose is 5,000 units, 1–3 times daily, every 9 days. This drug can be used after the patient has taken menotropin treatment.
- Purpose: Increase sperm count and testosterone in men
Mature: 500–1,000 units, 2–3 times a week for 3 weeks.
- Purpose: Treating cryptorchidism in boys
Children ages 4–9 years: 4,000 units, 3 times a week for 3 weeks, or 5,000 units, every 2 days, 4 injections.
How to Use Human Chorionic Gonadotropin Correctly
Human chorionic gonadotropin (hCG) is only available as an injection. Follow the instructions and recommendations given by the doctor during treatment with human chorionic gonadotropin.
The hCG injection will be given under the skin (subcutaneous/SC) or into the muscle (intramuscular/IM) by a doctor or medical officer under the supervision of a doctor.
Be sure to check with your doctor regularly while using human chorionic gonadotropin so that the doctor can monitor the progress of the condition.
Interaction of Human Chorionic Gonadotropin with Other Drugs
An interaction effect that can occur if hCG is used with other drugs is the decreased effect of hCG when used with ganirelix.
In addition, the use of human chorionic gonadotropin can also interfere with the results of the LH hormone test.Lutenizing hormone) or FSH (follicle-stimulating hormone).
To prevent interaction effects, always tell your doctor if you are taking any medications, supplements or herbal products.
Side Effects and DangersHuman Chorionic Gonadotropin
The following are some of the side effects that can occur after using human chorionic gonadotropin (HCG):
- Headache
- Nausea, vomiting, stomach pain, swollen stomach
- Pain, swelling, bruising, or irritation at the injection site
- Bleeding from the vagina outside of the menstrual cycle
Check with your doctor if the side effects above do not subside. Immediately see a doctor if an allergic reaction occurs to a drug or a more serious side effect occurs, such as: ovarian hyperstimulation syndrome (OHSS). Some complaints that can indicate the occurrence of this condition are:
- Swelling in the lower abdomen and hips
- Nausea and vomiting that is very severe and continuous
- Sudden drastic weight gain
- Very little urine output
- Chest pain, sudden severe headache, weakness on one side of the body, or slurred speech
In addition, the use of hCG can also increase the risk of early puberty in boys.