Triprolidine is a medication to relieve allergy symptoms. can be found in cough medicine or cold medicine products, in combination with other drugs.
Triprolidine belongs to the first generation of antihistamines. This drug works by blocking the action of histamine and binding histamine to its receptors. Histamine is a substance in the body that will cause an allergic reaction when the body is exposed to allergens.
The way triprolidine works will relieve a number of complaints due to allergic reactions, such as sneezing, runny nose, or itching. The use of triprolidine can cause drowsiness.
Triprolidine trademark: Actifed, Alerfed, Lapifed, Librofed, Mezinex Antitussive, Profed, Quantidex
What is triprolidine
| group | Limited over-the-counter drugs |
| Category | Antihistamines |
| Benefit | Relieves allergy symptoms |
| Consumed by | Adults and children |
| Triprolidine for pregnant and lactating women | Category N: Not categorized. Triprolidine may be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Drug form | Tablets and syrup |
Warnings Before Taking Triprolidine
There are several things you should pay attention to before taking triprolidine, including:
- Do not take triprolidine if you are allergic to this drug.
- Consult a doctor if you have or are currently suffering from asthma, emphysema, heart disease, liver disease, hypertension, seizures, hyperthyroidism, enlarged prostate gland, peptic ulcer, or glaucoma.
- Some cough syrup products containing triprolidine may contain added sugar or aspartame, talk to your doctor about their use if you have diabetes or phenylketonuria.
- Do not drive a vehicle or do activities that require alertness after taking triprolidine, because this medicine may cause drowsiness, dizziness, or blurred vision.
- alcoholic beverages
- Avoid doing strenuous exercise or activities that can make you hot, because this drug has the risk of causing heat stroke.
- Talk to your doctor first if you want to use triprolidine with medications, supplements, or herbal products.
- Talk to your doctor about using triprolidine if you are pregnant, breastfeeding, or planning a pregnancy.
- See your doctor right away if you have an allergic drug reaction, serious side effect, or overdose after taking triprolidine.
Dosage and Rules for Use of Triprolidine
The triprolidine dose varies in each patient, depending on the patient's age. In general, the following is the dose of triprolidine to relieve allergy symptoms based on the patient's age:
- Mature: 2.5 mg, every 4–6 hours. The maximum dose is 10 mg per day.
- 4 months old until 2 years: 0.313 mg, every 4–6 hours. The maximum dose is 1.252 mg per day.
- Children aged 2–4 years: 0.625 mg, every 4–6 hours. The maximum dose is 2.5 mg per day.
- Children aged 4-5 years: 0.938 mg, every 4–6 hours. The maximum dose is 3.744 mg per day.
- Children aged 6–11 years: 1.25 mg, every 4–6 hours. The maximum dose is 5 mg per day.
How to Take Triprolidine Correctly
Read the instructions on the packaging before taking any medicinal product that contains triprolidine. If in doubt, discuss and ask your doctor to get the dose and duration of treatment that suits your condition.
Triprolidine can be taken before or after meals. If you are taking triprolidine in tablet form, use plain water to swallow the tablet. If you take triprolidine in syrup form, be sure to use the measuring spoon provided in the package for the correct dosage.
If you forget to take triprolidine, take it as soon as you remember. If it is near the time of your next dose, ignore the missed dose. Do not double the triprolidine dose to make up for a missed dose.
Do not use this medicine for 7 days in a row. See a doctor immediately if symptoms do not subside within 6 days or other symptoms appear, such as fever, dizziness, or a skin rash.
Store triprolidine in a place away from direct sunlight. Keep this medicine out of reach of children.
Triprolidine Interactions with Other Drugs
There are several interactions that can occur if triprolidine is taken with certain drugs, including:
- Increased risk of occurrence heat stroke if taken with topiramate or zonisamide
- Enhanced sedative (sedating) effect of antidepressant drugs
- Increased risk of side effects, such as dizziness, drowsiness, confusion, difficulty concentrating, and trouble breathing, when used with ketamine
- Increased risk of stomach and intestinal irritation when used with potassium supplements
- Increased risk of undetected hearing loss due to side effects of aminoglycoside antibiotics
In addition, the sedative effect of this drug will increase if taken with alcoholic beverages.
Triprolidine Side Effects and Dangers
Some of the side effects that can occur after taking triprolidine are:
- Dizzy
- Drowsiness
- Headache
- Dry mouth, nose or throat
- Nausea or vomiting
- Loss of appetite
- Constipation
- Blurred vision
In addition, you should see a doctor immediately if you experience an allergic reaction to the drug or a more serious side effect, such as hallucinations, restlessness, nervousness, ringing in the ears, difficulty urinating, fast or irregular heartbeat, or seizures.