Arginine or L-arginine is an amino acid that can be used in the treatment of chest pain (angina .).), high blood pressure, preeclampsia, erectile dysfunction, peripheral arterial disease, inflammation of the gastrointestinal tract in newborns, and recovery after surgery.
Naturally, arginine can be obtained by regularly consuming foods that contain protein, such as red meat, chicken, fish, dairy products, soy, whole wheat, or nuts.
In the body, arginine will be converted into nitric oxide. Nitric oxide acts to widen blood vessels, so blood can flow more smoothly. In addition, arginine also plays a role in stimulating the release of growth hormone, insulin, and other compounds in the body.
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What is Arginine
| group | Prescription drugs |
| Category | Amino acid supplements |
| Benefit | Used in the treatment of angina, high blood pressure, erectile dysfunction, or peripheral artery disease |
| Used by | Adults and children |
| Arginine for pregnant and lactating women | Category B:Animal studies have not shown any risk to the fetus, but there are no controlled studies in pregnant women. Arginine can be absorbed into breast milk. For breastfeeding mothers, consult a doctor before using this drug. |
| Drug form | Inject |
Warning Before Using Arginine
Follow the doctor's recommendations and advice during treatment with arginine. Before using this drug, you need to pay attention to the following points:
- Do not use arginine if you are allergic to this drug. Tell your doctor about any allergies you have.
- Tell your doctor if you have or are currently suffering from kidney disease, low blood pressure (hypotension), asthma, cirrhosis, recent heart attack, herpes, electrolyte imbalance, or recent surgery.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- Tell your doctor if you are taking certain medications, supplements, or herbal products.
- See your doctor right away if you have an allergic reaction or overdose after using arginine.
Dosage and Rules for Use of Arginine
Arginine will be given by injection through a vein (intravenous / IV) by a doctor or medical officer under the supervision of a doctor. The following are common doses of arginine based on the patient's age:
- Adults and children weighing 60 kg:30 grams as a single dose, given by infusion over 30 minutes.
- Children weighing <60 kg: 0.5 gram/kg body weight, given by infusion over 30 minutes.
How to Use Arginine Correctly
Arginine will be given directly by a doctor or medical officer under the supervision of a doctor. The drug will be injected into a vein (intravenous / IV).
During treatment with arginine, the doctor will measure blood pressure regularly to ensure the condition and response to therapy. Follow your doctor's advice before and during treatment with arginine.
Arginine Interactions with Other Drugs
The following are the effects of drug interactions that may occur if arginine is used together with other drugs:
- Increased risk of hypoglycemia when used with anti-diabetic drugs, such as glimepiride
- Increased risk of bleeding if used with anticoagulant drugs, such as warfarin
- Increased risk of hypotension if used with antihypertensive drugs, nitrates, isoproterenol, or sildenafil
- Increased risk of developing hyperkalemia when used with potassium-sparing diuretic drugs, such as spironolactone or amiloride
Arginine Side Effects and Dangers
If used according to the instructions for use and the recommended dosage, arginine supplements are generally safe and rarely cause side effects. However, in some conditions, side effects can appear in the form of:
- Burning, swelling, numbness, or soreness at the injection site
- Bloating or stomach pain
- Headache or dizziness
- Nausea or vomiting
Check with your doctor if you experience any of the side effects mentioned above. Call your doctor right away if you experience an allergic reaction to any medication after using arginine.