Thiamphenicol is an antibiotic drug to treat diseases caused by bacterial infections. Some diseases that can be treated by this drug are typhus, gonorrhea, meningitis, respiratory tract infections, and digestive tract infections.
Thiamphenicol is a broad-spectrum antibiotic that works by inhibiting the growth of bacterial cells that cause infection. This medicine should only be used according to a doctor's prescription.
Thiamphenicol trademarks: Biothicol, Canicol, Dexycol, Dionicol, Fosicol, Fusaltrax, Genicol, Lacophen, Lithicol, Medtyaphen, Mesacol, Miracap, Nilacol, Phenobiotic, Phenomed, Promixin, Riamycin, Rindofen, Sendicol, Sithiam, Solathim, Thiamfilex, Thiamex, Thiamfilex, Thislacol, Tiphutic-500, Troviakol, Zenicol
What's that Thiamphenicol
| group | Prescription drugs |
| Category | Antibiotics |
| Benefit | Overcoming bacterial infections |
| Consumed by | Adults and children |
| Thiamphenicol for pregnant and lactating women | Category N:Not categorized. Thiamphenicol can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first. |
| Drug form | Capsules, caplets and dry syrup |
Precautions Before Taking Thiamphenicol
Thiamphenicol should not be used carelessly. Here are some things you need to pay attention to before taking thiamphenicol:
- Do not take thiamphenicol if you are allergic to this drug.
- Do not take this medicine if you have or have had a bone marrow or blood disorder.
- Tell your doctor if you have or have had a severe infection, G6PD deficiency, kidney or liver disease.
- Tell your doctor if you plan to vaccinate with live vaccines while you are taking thiamphenicol, as this medicine may decrease the effectiveness of the vaccine.
- Avoid using this drug in newborns (under 2 weeks of age) and premature babies because it can cause gray baby syndrome.
- Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
- Tell your doctor if you are taking certain medications, supplements, or herbal products.
- See your doctor right away if you have an allergic reaction or overdose after taking thiamphenicol.
Dosage and Instructions for Use of Thiamphenicol
The following are general doses of thiamphenicol based on the condition to be treated and the age of the patient:
Condition: Bacterial infections and sexually transmitted diseases
- Mature: 1500 mg/day, can be divided into several doses. The dose may be increased to 3,000 mg/day for severe infections.
- Children: 30–100 mg/kg/day.
Condition: Gonorrhea
- Mature: 2,500 mg/day for 1–2 days, or 2,500 mg on the first day and then 2,000 mg/day for 4 days.
How to Consume Thiamphenicol correctly
Always follow the doctor's instructions and read the information on the medicine package before taking thiamphenicol.
Take thiamphenicol according to the dose given by the doctor. Do not increase or decrease the dose, or stop taking the drug sooner than the prescribed time without consulting your doctor first.
Thiamphenicol can be taken on an empty stomach. It is recommended to take thiamphenicol 1 hour before eating or 2 hours after eating. Swallow thiamphenicol capsules or caplets whole with the help of water.
To take thiamphenicol dry syrup form, mix the drug with water according to the recommended dose. Use a measuring cup so that the volume of water mixed is just right.
Take thiamphenicol at the same time every day. If you forget to take thiamphenicol, do it as soon as you remember if the interval between the next consumption is not too close. If it is close, ignore it and do not double the dose.
Patients who take thiamphenicol in the long term due to certain conditions are advised to undergo regular blood tests. This action is carried out by doctors to monitor the patient's health condition and the effectiveness of antibiotics.
Store thiamphenicol at room temperature, in a dry place, and away from sunlight. Keep this medicine out of reach of children.
Thiamphenicol and Other Drug Interactions
The following are some of the effects of interactions that may occur if thiamphenicol is used together with other medicines:
- Increased risk of bone marrow decline if used with drugs that inhibit bone marrow function
- Increases the effect of anticoagulant drugs, antidiabetic drugs, or anticonvulsant drugs, such as phenytoin
- Increase metabolism of thiamphenicol when used with phenobarbital or rifampicin
Side Effects and Dangers Thiamphenicol
There are several side effects that can occur after taking thiamphenicol, including:
- Headache
- Nauseous
- Throw up
- Diarrhea
- Ulcer
- Inflammation of the tongue (glossitis)
- Mood changes
- Gray baby syndrome
In addition, long-term use of thiamphenicol can increase the risk of bleeding and optic neuritis.
Check with your doctor if these side effects don't get better or get worse. See your doctor immediately if you have serious side effects or an allergic reaction to the drug, which can be characterized by swelling of the lips or eyelids, an itchy rash on the skin, or difficulty breathing.